Sacheen Cruz Littlefeather (born Marie Louise Cruz; November 14, 1946 – October 2, 2022) was an American actress, model, and Native American civil rights activist. Littlefeather was born to a Native American (Apache and Yaqui) father and a European American mother.

During the 1969 occupation of Alcatraz, she became involved in the Native American activist community. Littlefeather represented Marlon Brando at the 45th Academy Awards in 1973, where she—on Brando's behalf—declined the Best Actor award that he won for his performance in The Godfather. The favorite to win, Brando boycotted the ceremony as a protest against Hollywood's portrayal of Native Americans and to draw attention to the standoff at Wounded Knee.