Ali Mosaffa (علی مصفا) was born in Tehran, Iran. His father, Mozaher Mosaffa is a renowned Persian poet and professor of Persian literature at the University of Tehran (UT).

Mosaffa mother, Amir Banoo Karimi is also a leading scholar and professor of Persian literature at the University of Tehran (UT) and the eldest daughter of the legendary Persian poet, Amiri Firuzkuhi. As a child, Ali Mosaffa discovered his interest in story writing and english, contributing to his fluency in the language. He is a graduate of Civil Engineering from the University of Tehran (UT) where he showed an interest in acting; making his debut in the 1991 film, Omid.