Leesa, the daughter of an artist and a college professor, grew up in Austin, Texas. She studied broadcast journalism at Texas Tech and acting at the Stella Adler Studio in Los Angeles, CA .

Leesa has a vast cult following for her role as Victoria in Troma Entertainment's Class of Nuke 'Em High Parts 2 and 3 and also appeared in Return To Nuke 'Em High. She acted in Troma's television series Troma's Edge along with Lloyd Kaufman and Debbie Rochon. She co-starred in Travis Campbell's Slaughter Daughter as Phyllis Adjani as an eccentric mother who drives her daughter to insanity.