Born Darlene Wright in Los Angeles in 1938, she began her career as lead singer with the vocal trio, The Blossoms. After a spell as regulars on ABC TV's variety show Shindig! (1964) in the early 60s, the trio went on to sing backup on a variety of Elvis Presley recordings, and even backed him on his 1968 NBC-TV special Elvis: The Comeback Special (1968).

For a while, they backed Tom Jones during some of his Las Vegas shows. The Blossoms have the rare distinction of recording a number one hit without ever receiving any credit. Years before the advent of Milli Vanilli, Darlene Love, Fanita James and Gracie Nitzsche sang vocals on the Gene Pitney-penned song "He's a Rebel" that was championed as The Crystals' first (and only) No.