Born in Teramo, Italy, Di Pasquale went on to study with mezzo-soprano Marina Gentile and received a diploma with the highest marks at the Conservatory of Rodi Garganico. He later studied with Elio Battaglia and Regina Resnik and won a scholarship to the International Competition “Vinas” in Barcelona and won the International Competition “Toti Dal Monte” in Treviso.

In 1995 he was selected to play the role of Don Alfonso in “Così Fan Tutte” for the Foundation “W. Walton” and in 1998 he won the VII International Competition “S. and G.