Claire Bretécher (17 April 1940 – 10 February 2020) was a French cartoonist, known particularly for her portrayals of women and gender issues. Her creations included Les Frustrés, and the unimpressed teenager Agrippine.

Bretécher was born in Nantes and got her first break as an illustrator when she was asked to provide the artwork for Le facteur Rhésus by René Goscinny for L'Os à moelle in 1963. She went on to work for several popular magazines and in 1969 invented the character "Cellulite". In 1972 she joined Gotlib and Mandryka in founding the Franco-Belgian comics magazine L'Écho des savanes.