Chen Sisi (陈思斯) is a Chinese actress. She graduated from the Acting Department of the Central Academy of Drama.

In 1993, she acted in her first television series Blue Yearning (蓝色的向往). She began studying acting at the The Central Academy of Drama in 2002. In 2005, she made her official debut in the television series If the Moon Has Eyes (如果月亮有眼睛).